Jacek Sikora has over 10 years experience with Proteomics. He completed his M.S. in biotechnology in 2000 from Maria Curie-Sklodowska University in Lublin, Poland where he studied localization of proteins in yeast mitochondria. In January 2001, he joined the newly established Mass Spectrometry Core Lab in Institute of Biochemistry and Biophysics (ibb.waw.pl), Polish Academy of Science in Warsaw, Poland where he was responsible for implementation protein/peptide identification procedures. Jacek worked in the proteomics core until 2010 where was involved in many collaboration projects which used mass spectrometry in qualitative as well as quantitative analyses. His Ph.D. thesis focused on mass spectrometry based, label free, quantitative analysis of yeast mitochondria proteins, using the LTQ-FT mass spectrometer. After receiving his Ph.D., he joined Steve Kron’s laboratory at Department of Molecular Genetics and Cell Biology, University of Chicago where he received extensive cancer biology training. In 2014 he started working at the Proteomics Center of Excellence and Core Facility at Northwestern University where he was initially responsible for triple-quadrupole mass spectrometry profiling of PTM on histones. Jacek currently uses top-down proteomics as part of National Resource for Translational and Developmental Proteomics (nrtdp.northwestern.edu).